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	Human endothelial cells exposed to oxidative stress. The nuclei are stained with PI (red), Green is complement C3 and Blue is MBL (mannose binding lectin).
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Friedman M, Wang SY, Stahl GL, Johnson RG, Sellke FW.
Altered ß-adrenergic and cholinergic pulmonary vascular responses after cardiopulmonary bypass.
J. Appl. Physiol.1995;79:1998-2006

Amsterdam EA, Stahl GL, Pan H-L, Rendig SV, Fletcher MP, Longhurst JC.
Limitation of reperfusion injury by a monoclonal antibody to C5a during myocardial infarction in pigs.
American Journal of Physiology 1995; 268:H448-H457 — Download PDF

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1996
Lennon PF, Collard CD, Morrissey MA, Stahl GL.
Complement mediated loss of endothelium-dependent relaxation of rabbit thoracic aorta: Mechanisms, recovery, and gender differences.
American Journal of Physiology 1996;270:H1924-H1932

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1997
Collard CD, Vakeva AP, Bukusoglu C, Zund G, Sperati CJ, Colgan SP and Stahl GL.
Reoxygenation of hypoxic human umbilical vein endothelial cells activates the classic complement pathway.
Circulation 1997; 96:326-33

Stahl GL, Morse DS, Martin SL.
Eicosanoid production from porcine neutrophils and platelets: Differential production with various agonists.
American Journal of Physiology (Cell Physiology) 1997; 272:C1821-8

Zund G, Uezono S, Stahl GL, Dzus AL, McGowan FX, Hickey PR, Colgan SP.
Hypoxia enhances induction of endothelial ICAM-1: Role for metabolic acidosis and proteasomes.
American Journal of Physiology (Cell Physiology) 1997; 273:C1571-80 — Download PDF

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1998
Vakeva AP, Agah A, Rollins, SA, Matis LA, Li L and Stahl GL.
Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: Role of the terminal complement components and inhibition by anti-C5 therapy.
Circulation 1998; 97:2259-67

Tofukuji M, Stahl GL, Agah A, Metais C, Simons M and Sellke FW.
Anti-C5a monoclonal antibody reduces cardiopulmonary bypass and cardioplegia-induced coronary endothelial dysfunction.
Journal of Thoracic and Cardiovascular Surgery 1998; 116:1060-8

Lennon PF, Taylor CT, Stahl GL, Colgan SP.
Neutrophil-derived 5'AMP promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2b receptor activation.
Journal of Experimental Medicine 1998; 188:1433-43

Collard CD, Agah A, Stahl GL.
Complement activation following reoxygenation of hypoxic human endothelial cells: Role of intracellular reactive oxygen species, NF-.B and new protein synthesis.
Immunopharmacology 1998; 39:39-50 — Download PDF

Blume ED, Taylor CT, Lennon PF, Stahl GL, Colgan SP.
Activated endothelial cells elicit paracrine induction of epithelial chloride secretion: 6-keto-PGF1. is an epithelial secretagogue.
Journal of Clinical Investigation 1998; 102:1161-72 — Download PDF

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1999
Fitch JCK, Rollins S, Matis L, Alford B, Aranki S, Collard CD, Dewar M, Elefteriades J, Hines R, Kopf G, Kraker P, Li L, OHara R, Rinder C, Rinder H, Shaw R, Smith B, Stahl GL, Shernan S.
Pharmacology and biological efficacy of a recombinant, humanized, single chain antibody C5 complement inhibitor in patients undergoing coronary artery bypass graft surgery utilizing cardiopulmonary bypass.
Circulation 1999; 100:2499 - 2506

Collard CD, Bukusoglu C, Agah A, Colgan SP, Reenstra WR, Morgan BP and Stahl GL.
Hypoxia-induced expression of complement receptor type 1 (CR1, CD35) in human vascular endothelial cells.
American Journal of Physiology (Cell Physiology) 1999; 276:C450-C458

Collard CD, Agah A, Reenstra W, Buras J and Stahl GL.
Endothelial nuclear factor-kB translocation and vascular cell adhesion molecule-1 induction by complement: Inhibition with anti-human C5 therapy or cGMP analogues.
Arteriosclerosis, Thrombosis and Vascular Biology 1999; 19:2623-2629

Szebeni J, Fontana JL Wassef NM, Mongan PD, Morse DS, Dobbins DE, Stahl GL, Bunger R, Alving CR.
Hemodynamic changes induced by liposomes and liposome-encapsulated hemoglobin in pigs: A model for pseudo-allergic cardiopulmonary reactions to liposomes. Role of complement and inhibition by soluble CR1 and anti-C5a antibody.
Circulation 1999; 99:2302-9

Park KW, Tofukuji M, Metais C, Comunale ME, Dai HB, Simons M, Stahl GL, Agah A, Sellke FW.
Attenuation of endothelium-dependent dilation of pig pulmonary arterioles after cardiopulmonary bypass is prevented by monoclonal antibody to complement C5a.
Anesthesia and Analgesia 1999; 89:42-8

Collard CD, Lekowski R, Jordan JE, Agah A and Stahl GL.
Complement activation following oxidative stress (REVIEW).
Molecular Immunology 1999; 36:941-8 — Download PDF

Tofukyji M, Metais C, Collard CD, Morse DS, Stahl GL, Nelson DP, Li J, Simons M, Sellke FW.
Effect of sialyl Lewis. -oligosaccharide on myocardial and cerebral injury in the pig.
Annals of Thoracic Surgery 1999; 67:112-9 — Download PDF

Clish CB, O.Brien JA, Gronert K, Stahl GL, Petasis NA, Serhan CN.
Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo.
Proceedings of the National Academy of Sciences 1999; 96:8247-52 — Download PDF

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2000
Tofukuji M, Stahl GL, Matais C, Tomita M, Agah A, Bianchi C, Fink MP, and Sellke FW.
Mesenteric dysfunction after extracorporal circulation: Role of complement C5a.
Annals of Thoracic Surgery 2000; 69:799-807

Zhou W, Farrar CA, Abe K, Pratt JR, Marsh JE, Wang Y, Stahl GL and Sacks SH.
Predominant role of C5b-9 in renal ischemia/reperfusion injury.
Journal of Clinical Investigation 2000; 105:1363-71

Agah A, Montalto MC, Kiesecker CL, Morrissey M, Grover M, Whoolery KL, Rother RP and Stahl GL.
Isolation, characterization and cloning of porcine complement component C7.
Journal of Immunology 2000; 165:1059-65 — Download PDF

Collard CD, Vakeva A, Morrissey MA, Agah A, Rollins SA, Reenstra WR, Buras JA, Meri S, and Stahl GL.
Complement activation following oxidative stress: Role of the lectin complement pathway.
American Journal of Pathology 2000; 156:1549-56 — Download PDF

Buras JA, Stahl GL, Svoboda KS, Reenstra WR.
Hyperbaric oxygen down-regulates ICAM-1 expression induced by hypoxia and hypoglycemia: the role of NOS.
American Journal of Physiology (Cell Physiology) 2000; 278:C292-C302 — Download PDF

Qui F-H, Wada K, Stahl GL, Serhan CN.
IMP and AMP deaminase in reperfusion injury down-regulates neutrophil recruitment.
Proceedings of the National Academy of Sciences 2000; 97:4267-72 — Download PDF

Szebeni J, Baranyi L, Savay S, Bodo M, Morse DS, Basta M, Stahl GL, Bunger R, Alving CR.
Liposome-induced pulmonary hypertension in pigs: properties and mechanism of a complement-mediated pseudoallergic reaction.
American Journal of Physiology (Heart and Circulatory Physiology) 2000; 279:H1319-28 — Download PDF

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2001
Wada K, Montalto MC, Stahl GL.
Inhibition of complement C5 reduces local and remote organ injury after intestinal ischemia/reperfusion in the rat.
Gastroenterology 2001; 120:126-33

Wada K, Qiu F-H, Stahl GL, Serhan CN.
Inosine monophosphate (IMP) and aspirin-triggered 15-epi-lipoxin A4 act in concert to regulate neutrophil trafficking: Additive actions of two new endogenous anti-inflammatory mediators.
Journal of Hematotherapy and Stem Cell Research 2001; 10:75-9

Stahl GL.
Reperfusion injury in surgery. Role of the endothelium, oxidative stress and complement activation (Invited review).
New Surgery 2001; 1:62-6

Agah A, Montalto MC, Young K, Stahl GL.
Isolation, cloning and functional characterization of porcine mannose-binding lectin.
Immunology 2001; 102:338-43 — Download PDF

Montalto MC, Collard CD, Buras JA, Reenstra WR, McClaine R, Geis D, Rother RP, Stahl GL.
A keratin peptide inhibits mannose-binding lectin.
Journal of Immunology 2001; 166:4148-53 — Download PDF

Collard CD, Montalto MC, Reenstra WR, Buras JA, Stahl GL.
Endothelial oxidative stress activates the lectin complement pathway: role of cytokeratin1 (CK1).
American Journal of Pathology 2001; 159:1045-54 — Download PDF

Jordan JE, Montalto MC, Stahl GL.
Inhibition of mannose binding lectin reduces postischemic myocardial reperfusion injury.
Circulation 2001; 104:1413-8 — Download PDF

Roos A, Bouwman LH, van Gijlswijk-Janssen DJ, Faber-Krol MC, Stahl GL, Daha MR.
Human IgA activates the complement system via the mannan-binding lectin pathway.
Journal of Immunology 2001; 167: 2861-8 — Download PDF

Lekowski R, Collard CD, Reenstra WR, Stahl GL.
Ulex europaeus agglutinin II (UEA II) is a novel and potent inhibitor of complement activation.
Protein Science 2001; 10:277-84 — Download PDF

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2002
Zhao H, Wakamiya N, Suzuki Y, Hamonko MT, Stahl GL.
Identification of human mannose binding lectin (MBL) recognition sites for novel inhibitory antibodies.
Hybridoma and Hybridomics 2002; 21:25-36

Zhao H, Montalto MC, Pfeiffer KJ, Hao L, Stahl GL.
Murine model of gastrointestinal ischemia associated with complement dependent injury.
Journal of Applied Physiology 2002; 93:338-45 — Download PDF

Collard CD, Park KA, Montalto MC, Alipati S, Buras JA, Stahl GL, Colgan SP.
Neutrophil-derived glutamate regulates vascular endothelial barrier function.
Journal of Biological Chemistry 2002; 277:14801-11 — Download PDF

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2003
Bhole DL, Stahl GL.
Therapeutic potential of targeting the complement cascade in critical care medicine.
Journal of Critical Care Medicine (Invited Review) 2003; 31:s97-s104 — Download PDF

Zhao H, Miller M, Pfeiffer K, Buras JA, Stahl GL.
Anoxia and reoxygenation of human endothelial cells decreases ceramide glucosyltransferase expression and activates caspases.
FASEB Journal 2003; express article 10.1096/fj.02-0806fje. Published online February 5, 2003. FASEB Journal 2003;17:723-4 — Download PDF

Jain A, Batista EL, Serhan CN, Stahl GL, Van Dyke TE.
Role for periodontitis in the progression oflipid depostion in an animal model.
Infection and Immunity 2003; 71:6012-8 — Download PDF

Lawrence DW, Bruyninckx WJ, Louis DM, Stahl GL, Parkos CA, and Colgan SP.
Antiadhesive role of apical decay-accelerating factor (CD55) in human neutrophil transmigration across mucosal epithelia.
Journal of Experimental Medicine 2003: 198:999-1010 (cover issue) — Download PDF

Serhan CN, Jain A, Marleau S, Clish C, Kantarci A, Behbehani B, Colgan SP, Stahl GL, Merched A, Petasis NA, Chan L, Van Dyke TE.
Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators.
Journal of Immunology 2003; 171:6856-65 (cover issue) — Download PDF

Stahl GL, Xu Y, Hao L, Miller M, Buras JA, Fung M, Zhao H.
Role for the alternative complement pathway in ischemia/reperfusion injury.
American Journal of Pathology 2003; 162:449-55 (Commentary provided by Riedemann RC and Ward PA. Complement in Ischemia Reperfusion Injury. Am J Pathol 2003;162:363-7) — Download PDF — Download Commentary PDF

Montalto MC, Hart ML, Jordan JE, Wada K, Stahl GL.
Role for complement in mediating intestinal nitric-oxide synthase2 and superoxide dismutase expression.
American Journal of Physiology: Gatrointestinal and Liver Physiology 2003; 285:G197-206 — Download PDF

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2004
Ohira T, Bannenberg G, Arita M, Takahashi M, Ge Q, Van Dyke TE, Stahl GL, Serhan CN, Badwey JA.
A stable aspirin-triggered lipoxin A4 analog blocks phosphorylation of leukocyte specific protein 1 in human neutrophils.
Journal of Immunology 2004; 173:2091-8 — Download PDF

Walsh MC, Hart ML, Bourcier TM, Bhole D, Takahashi M, Stahl GL.
Role of complement in myocardial ischemia and infarction.
In: Szebeni J, editor. The Complement System. Novel Roles in Health and Disease. Kluwer Academic Publishers. Boston, Massachusetts, 2004; Chapter 19, pages 421-36

Pachori AS, Melo LG, Hart ML, Noiseux N, Zhang L, Morello F, Solomon SD, Stahl GL, Pratt RE, Dzau VJ.
Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury.
Proceedings of the National Academy of Sciences 2004; 101:12282-7 — Download PDF

Bhole D and Stahl GL.
Molecular basis for complement component 6 (C6) deficiency in rats and mice.
Immunobiology 2004; 209:559-68 — Download PDF

Khan TA, Bianchi C, Voisine P, Feng J, Hart M, Takahashi M, Stahl G, Sellke FW.
Reduction of myocardial reperfusion injury by aprotinin after regional ischemia and cardioplegic arrest.
Journal of Thoracic and Cardiovascular Surgery 2004; 128:602-8 — Download PDF

Hart ML, Walsh MC, Stahl GL.
Initiation of complement activation following oxidative stress. In vitro and in vivo observations.
Molecular Immunology 2004; 41:165-71 — Download PDF

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2005
Walsh MC, Bourcier T, Takahashi K, Shi L, Busche MN, Rother RP, Solomon SD, Ezekowitz RAB, Stahl GL.
Mannose binding lectin is a regulator of inflammation that accompanies myocardial ischemia and reperfusion injury.
Journal of Immunology 2005; 175: 541-6 — Download PDF

Buras J, Rice L, Orlow D, Pavlides S, Reenstra WR, Ceonzo K, Stahl GL.
Inhibition of C5 or absence of C6 protects against sepsis mortality.
Immunobiology 2005; 209:629-35 — Download PDF

Rice L, Orlow D, Ceonzo K, Stahl GL, Tzianabos AO, Wada H, Aird WC,
CpG oligodeoxynucleotide protection in polymicrobial sepsis is dependent on IL-17.
Journal of Infectious Disease. 2005; 191:1368-76 — Download PDF

Hart ML, Ceonzo KA, Shaffer LA, Takahashi K, Rother R, Reenstra WR, Buras JA, Stahl GL.
Gastrointestinal ischemia-reperfusion injury is lectin complement pathway dependent without involving C1q.
Journal of Immunology 2005; 174:6373-80 (cover issue) — Download PDF

Peng T, Hao L, Madri J, Su X, Elias JA, Stahl G, Squinto S, Wang Y.
Role of C5 in the development of airway inflammation, airway hyperresponsiveness and ongoing airway response.
Journal of Clinical Investigation 2005; 115: 1590-1600 — Download PDF

Cho JH, Fraser IP, Fukase K, Kusumoto S, Stahl GL, Ezekowitz RAB.
Binding specificity and activity of human Peptidoglycan Recognition Protein-S (PGRP-S): role in neutrophil-mediated innate immunity.
Blood 2005; 106:2551-8 — Download PDF

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2006
Ceonzo K, Gaynor A, Shaffer L, Kojima K, Vacanti CA, Stahl GL.
Polyglycolic acid-induced inflammation: Role of hydrolysis and resulting complement activation.
Tissue Engineering 2006; 12:301-8

Harboe M, Garred P, Borgen MS, Stahl GL, Roos A, Mollnes TE.
Design of a complement lectin pathway specific activation system applicable at low serum dilutions.
Clinical and Experimental Immunology 2006;144:512-20

Roos A, Rastaldi MP, Calvaresi N, Oortwifn BD, Schlagwein N, van Gijlswijk-Janssen DJ, Stahl GL, Matsushita M, Fujita T, van Kooten C, Daha MR.
Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease.
Journal of the American Society of Nephrology 2006; 17:1724-34

Costa C, Zhao L, Shen Y, Su X, Hao L, Colgan SP, Stahl GL, Zhou T, Wang Y.
Role of complement component C5 in cerebral ischemia/reperfusion injury.
Brain Research 2006; 1100:142-51

McMullen ME, Hart ML, Walsh MC, Buras J, Takahashi K and Stahl GL.
Mannose binding lectin binds IgM to activate the lectin complement pathway in vitro and in vivo.
Immunobiology 2006; 211:759-66 (Epub July 28, 2006) (cover issue)

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2007
Ganter MT, Brohi K, Cohen MJ, Shaffer LA, Walsh MC, Stahl GL, Pittet JF.
Role of the alternative pathway in the early complement activation following major trauma.
Shock 2007; in press

Peckham RM, Handrigan MT, Bentley TB, Galabella MJ, Chrovian AD, Stahl GL, Tsokos GC.
C5-blocking antibody reduces fluid requirements and improves responsiveness to fluid infustion in hemorrhagic shock managed with hypotensive sesuscitation.
Journal of Applied Physiology 2007; in press

You Z, Yang J, Takahshi K, Yager P, Kim H-H, Qin T, Stahl GL, Ezekowitz A, Carroll M, Whalen M.
Reduced tissue damage and improved recovery of motor function after traumatic brain injury in mice deficient in complement component C4.
Journal of Cerebral Blood Flow & Metabolism 2007; in press

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